Chinese COVID-19 vaccine shows promising trial results: study
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The latest on COVID-19:


--The Chinese mainland registered 19 new COVID-19 cases on Saturday, of which four were domestically transmitted, all reported in Xinjiang Uygur Autonomous Region and 15 were imported, the National Health Commission said on Sunday.


--From August 17, all passengers from Hong Kong to Beijing by air are required to show their nucleic acid test results issued by the testing agency of the HKSAR government, and the result must be negative within 7 days.


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A staff member displays a sample of the COVID-19 inactivated vaccine at a vaccine production plant of China National Pharmaceutical Group Co., Ltd. (Sinopharm) in Beijing, capital of China, April 10, 2020. (Photo/Xinhua)

An inactivated COVID-19 vaccine candidate developed by China is safe and generates an immune response, according to data from clinical trials published in The Journal of the American Medical Association this week.

The research paper provided an interim analysis of the phase-1 and phase-2 clinical trials of an inactivated COVID-19 vaccine developed by the Wuhan Institute of Biological Products under the China National Biotec Group (CNBG), affiliated to Sinopharm, and the Wuhan Institute of Virology under the Chinese Academy of Sciences.

The research involved data on 320 healthy volunteers aged between 18 and 59, of which 96 participated in phase-1 clinical trials and 224 participated in phase-2 trials.

The research reported geometric mean titers of neutralizing antibodies in the volunteers, who were separated into low-dose, medium-dose and high-dose groups.

The results showed that the vaccine effectively induced neutralizing antibodies in the volunteers and demonstrated good immunogenicity -- the ability of a substance to trigger an immune response.

The research paper also evaluated the safety of the vaccine, reporting that no serious adverse reactions were observed. The most common adverse reaction was pain at the injection site, followed by fever, both of which were mild and self-limiting.



Source: Xinhua, China Daily,People's Daily

Editor: Lv Yun